Chemistry of bioactive metabolites in sponges collected from Sabah waters / Ho Nina Ann Jin.
Material type:
TextPublication details: Kota Kinabalu, Sabah : Universiti Malaysia Sabah, 2005.Description: xiv, 84p. : ill. ; 30cmSubject(s): Dissertation note: Academic exercise (BSc.) -- Sekolah Sains dan Teknologi, Universiti Malaysia Sabah, 2005. Abstract: Porifera are the most primitive multicellular animals. An estimated 10,000 species of sponges are found in both marine and freshwater distributed around the world. Porifera, well known of their secondary metabolites, also show biological activities such as anti-inflammatory, antifungal, antibacterial, antitumor, and cytoxic activity. Hence, the functional roles of these secondary metabolites have been under study in recent decades. The seven species of marine sponges Haliclona sp., Spongia sp., Clathria sp., Gelliodes sp., Stylotella aurantium, Coelocarteria sp. and Asteropus sarassinorum collected from Sabah waters were extracted in hexane, 90% methanol and butanol crude extracts. All the extracts from seven species showed antibacterial activities against marine enviromental bacteria, Clostridium sordelli and Clostridium novyi. The long chain saturated hydrocarbon compound was isolated from the hexane extract of Haliclona sp. with the extract percentage of 7.89%. This compound showed antibacterial activity againts Clostridium sordelli.
| Item type | Current library | Home library | Call number | Vol info | Copy number | Status | Date due | Barcode | |
|---|---|---|---|---|---|---|---|---|---|
Academic Exercise
|
MAIN LIBRARY Main Library Research Collection | MAIN LIBRARY Main Library Research Collection | QD476.2 . N56 2005 (Browse shelf(Opens below)) | SST | 1 | Available | 1400006491 |
Diseliakan oleh Dr. Charles S. Vairappan.
Academic exercise (BSc.) -- Sekolah Sains dan Teknologi, Universiti Malaysia Sabah, 2005.
Includes Bibliographical References.
Porifera are the most primitive multicellular animals. An estimated 10,000 species of sponges are found in both marine and freshwater distributed around the world. Porifera, well known of their secondary metabolites, also show biological activities such as anti-inflammatory, antifungal, antibacterial, antitumor, and cytoxic activity. Hence, the functional roles of these secondary metabolites have been under study in recent decades. The seven species of marine sponges Haliclona sp., Spongia sp., Clathria sp., Gelliodes sp., Stylotella aurantium, Coelocarteria sp. and Asteropus sarassinorum collected from Sabah waters were extracted in hexane, 90% methanol and butanol crude extracts. All the extracts from seven species showed antibacterial activities against marine enviromental bacteria, Clostridium sordelli and Clostridium novyi. The long chain saturated hydrocarbon compound was isolated from the hexane extract of Haliclona sp. with the extract percentage of 7.89%. This compound showed antibacterial activity againts Clostridium sordelli.